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Journal articles
Local delamination in pharmaceutical blister packages • A thermomechanical theory on buckling of heat-sealed composite laminates in flexible packaging, TAPPI Journal July 2025
ABSTRACT: Pharmaceutical blister packages consist of cavities made from a thick polymeric form foil and a thin aluminum lid foil. Heat-sealing technology is usually used to bond the lid foil to the form foil. Occasionally, the sealed area shows buckling defects of the lid foil, which allow contamination to enter into the cavity. A contaminated product is a worst-case scenario for pharmaceutical production and must be avoided. We discuss a thermomechanical theory on buckling defects in blister packages and derive strategies to avoid these. The theory is based on the assumption that the seal of a blister packaging behaves like a laminate of thin composite layers under compressive load. Literature research on buckling of thin laminated films, thermal behavior of polymers, and seal strength of heat-sealed polymers provides the technical and physical background to elaborate the theory. The theory comprises three elements: an initial condition regarding thermal load and precedent defects; a buckling condition; and a crack propagation condition. The plausibility of the theory is verified using model calculations and heat-seal tests. The paper concludes with strategies against buckling of heat-sealed lid foils and an outlook on other applications in laminating and coating of polymer films.
Journal articles
Clarifiers for Polypropylene Film, The PLACE, December 2006
Clarifiers for Polypropylene Film, The PLACE, December 2006
Journal articles
Toughening Clear Polypropylene With Styrenic Block Copolymers
Toughening Clear Polypropylene With Styrenic Block Copolymers
Journal articles
Chemical Analysis of the Polyester/Metal Surface of a Delamination Failure
Chemical Analysis of the Polyester/Metal Surface of a Delamination Failure
Journal articles
Relationship of Rheological Behavior and Molecular Architecture of LDPE Designed for Extrusion Coating
Relationship of Rheological Behavior and Molecular Architecture of LDPE Designed for Extrusion Coating
Journal articles
Study of corrugated liner paper and bondability by hot-melt adhesives, TAPPI JOURNAL, September 1997, Vol. 80(9)
Study of corrugated liner paper and bondability by hot-melt adhesives, TAPPI JOURNAL, September 1997, Vol. 80(9)
Journal articles
The evolution of conductive coatings, TAPPI JOURNAL, December 1990, Vol. 73(12)
The evolution of conductive coatings, TAPPI JOURNAL, December 1990, Vol. 73(12)
Journal articles
Accelerated electron-cured, hot melt pressure-sensitive adhesives provide improved plasticizer and heat resistance, TAPPI JOURNAL, February 1991, Vol. 74(2)
Accelerated electron-cured, hot melt pressure-sensitive adhesives provide improved plasticizer and heat resistance, TAPPI JOURNAL, February 1991, Vol. 74(2)
Journal articles
The role of specific gravity for removal of hot melt adhesives in recyclable grades, TAPPI JOURNAL, September 1992, Vol. 75(9)
The role of specific gravity for removal of hot melt adhesives in recyclable grades, TAPPI JOURNAL, September 1992, Vol. 75(9)
Journal articles
Measurement and control of biaxially oriented films for coating, laminating, and packaging applications, TAPPI JOURNAL, April 1993, Vol. 76(4)
Measurement and control of biaxially oriented films for coating, laminating, and packaging applications, TAPPI JOURNAL, April 1993, Vol. 76(4)